Molecular Formula | C2HCl3O |
Molar Mass | 147.39 |
Density | 1.532 g/mL at 25 °C (lit.) |
Melting Point | <25 °C |
Boling Point | 107-108 °C (lit.) |
Flash Point | 66 °C |
Water Solubility | MAY DECOMPOSE |
Solubility | Chloroform, Hexanes |
Vapor Presure | 27mmHg at 25°C |
Appearance | Liquid |
Specific Gravity | 1.537 (20/4℃) |
Color | Clear colorless to light yellow |
Merck | 14,3053 |
BRN | 1209426 |
Storage Condition | 2-8°C |
Stability | Stable. Combustible. Incompatible with water, alcohols and oxidizing agents. Fumes in air. |
Sensitive | Moisture Sensitive |
Refractive Index | n20/D 1.46(lit.) |
Physical and Chemical Properties | Colorless and irritating liquid. boiling point 108~110 ℃ relative density 1.5315 refractive index 1.4591 solubility is miscible with ether. |
Use | For organic synthesis and pesticide, pharmaceutical intermediates |
Risk Codes | R35 - Causes severe burns R50 - Very Toxic to aquatic organisms |
Safety Description | S9 - Keep container in a well-ventilated place. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 1765 8/PG 2 |
WGK Germany | 2 |
RTECS | AO6650000 |
FLUKA BRAND F CODES | 19-21 |
TSCA | Yes |
HS Code | 29159000 |
Hazard Note | Corrosive/Moisture Sensitive |
Hazard Class | 8 |
Packing Group | II |
Raw Materials | Trichloroethylene Trichloroethylene Oxygen |
Downstream Products | trichloroacetyl chloride Carboprost methylate |
colorless and irritating liquid. Boiling point 108~110 deg C. The relative density was 1. 5315. Refractive index 4591. Can be miscible with ether, water, ethanol decomposition. Smoke in the air.
for the synthesis of vinyl insecticides, also used in wool felting finishing, bleaching, decolorization, preservation, sterilization, Disinfection.
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Use | dichloroacetyl chloride is an agent with antitumor and anticancer activity useful in the synthesis of substituted benzothiazoles. used in organic synthesis and pesticides, pharmaceutical intermediates used as intermediates in organic synthesis used in the synthesis of vinyl pesticides, also used in wool felting finishing, bleaching, decolorization, preservation, sterilization, Disinfection, etc. |
production method | a variety of process routes can be used in the preparation method. The reaction of dichloroacetic acid with chlorosulfonic acid, the reaction of chloroform with carbon monoxide catalyzed by anhydrous aluminum trichloride, the reaction of dichloroacetic acid with phosgene in dimethylformamide, and the oxidation of trichloroethylene can be obtained. Trichloroethylene and azobisisobutyronitrile (catalyst) were heated to 100 ° C., oxygen was introduced, and the reaction was carried out under 0.6MPa pressure. The temperature of the oil bath was maintained at 110 ° C., and the reaction was carried out for 10 hours. The by-product of the reaction, trichloroethylene oxide, can also be converted into dichloroacetyl chloride by reacting with amine compounds such as methylamine, triethylamine and pyridine. |
category | corrosive article |
toxicity grade | poisoning |
Acute toxicity | oral-rat LD50: 2460 mg/kg |
stimulation data | Skin-moderate in rabbits at 10 mg/24 h; eye-rabbit 50 μg severe |
flammability hazard characteristics | in case of open flame, high heat, flammable oxidant; Heat or water, acid Decomposition of toxic chloride gas |
storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; Stored separately from oxidants and acids |
extinguishing agent | Sand, carbon dioxide |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |